After a year of trying, one of the first drugs your doctor will likely put you on is Clomid (Clomiphene Citrate). An ovulatory regulator, Clomid can help stabilize and time your cycle. It is a great start, however there are a lot of issues with this therapy. Clomid can severely thin out your uterine lining, as well as change the cervical mucous. Both of which can actually make getting pregnant even harder! Even if the sperm meets the egg, it will not be able to properly attach to the uterine wall and you still will not be pregnant.
This is not to say that you will not be able to conceive on Clomid, because there are many people that have. It just means that you need to be sure that you are following proper monitoring procedures. I did not know anything about this issue when I first started, and the doctor that started me on it did not do the proper monitoring. So it is likely that the first few months I was on this drug, we were just wasting our time. When I switched doctors, I found out that the drug was making my lining almost half the size it should be for proper implantation!
What is the proper monitoring procedures? Internal ultrasounds are your best bet (especially when paired with blood monitoring). This way, your doctor can make sure you are making sufficient follicles and measure your lining at the same time. If caught soon enough, you can also go on another drug that will help increase the lining.
Another issue with Clomid is side effects. Obviously every woman is different and not every woman will experience all of the side effects of Clomid (if any at all). I had a very hard time with this drug. I felt absolutely INSANE on it. Crazy mood swings, hot flashes, dizziness, nausea, headaches, appetite changes, weight gain, jaw clenching, and speed-like effects were just a few of the side effects I dealt with. Some women also experience vision changes as well.
Clomid has a limited time of use. It is recommended that you do not stay on Clomid any longer than 6 months, so be sure that you are following the proper protocols so you can maximize your chances while you are on this drug, and hopefully will get your baby sooner rather than later!